Although the previous many studies showed that EGCG
induced growth arrest and apoptosis in human head and
neck squamous carcinoma cell lines, mitochondrial apoptogenic
factors in the cell death of a human laryngeal epidermoid
carcinoma of the larynx Hep2 cells by EGCG
treatment have yet to be elucidated. The present study
was undertaken to demonstrate the effects of caspases on
the relationship between the release of mitochondrial
pro-apoptotic molecules in Hep2 cells by EGCG treatment