The most common indication for performing bronchial challenges is to diagnose hyperresponsive airways. Subjects may
demonstrate normal baseline pulmonary function testing and show little or no response when administered a
bronchodilator, despite repeated complaints of respiratory symptoms (chest tightness, wheezing, cough). In such cases,
bronchial challenges can be used to confirm or rule out a diagnosis of hyperreactive airways.
Indications for bronchial challenges include the following: