Instrumental analysis professor vicki colvin
-hi work course there is lsrael analysis and this is week
-3 so where we are in the street from the class is really finishing up
-this week our discussion atomic spectroscopy now
-while we're talking about atomic spectroscopy this week we're gonna be
-going back and quantity details
-that how to calibrate spectrometers and most critically how to use them so that
-we minimize
-know their systematic and the random error so it's gonna be pretty
-on it week and we're gonna cover a variety of topics is shown here
-to be between seven and eight lectures and definitely definitely plan to
-practice the problems
-but the purpose and everything really doing this week
-really has to do with quality control and quality assurance
-so this is a pretty big topic in analytical chemistry right now
-here's a really good but that she can refer to you if you need to know more
-about
-or he might be responsible for to making procedures in your own laboratory
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-sep let's start by dfining
-quality when people say quality control and quality assurance
-whether the recapture and giving you two definitions here
-what ! i'm remarkable about both of these definitions
-is their brokers on the customer and
-if you notice in the ISO definition which is again a very long definition
-you also see in
-whether or not and measurement with those in need are provided service
-so the terps quality control and quality assurance
-I think quality control as the actions you take the things he would do
-as an analyst to ensure urinalysis is up high quality
-quality assurance a little bit more organizational
-responsibility its what is the organization doing to make
-really sure that their quality control measures are actually being followed
-so you might say quality control is what you should do
-and quality assurance is how you're guaranteeing the people in your
-organization
-actually following the rules so this diagram
-which comes from the book acuvue beginning it's adapted from where the
-figures
-I really like is it shoes you what would you do in
-analyst to really think about quality so let's take a moment and look at that
-so the first thing that you can notice is that we have
-a whole process analysis because from the methodology you're applying to the
-house itself
-to the results reported into whoever's using
-and so you can imagine that is kinda luchar the houses process
-and quality control measures comment each stage
-for example validation you could do you
-injury laboratory studies and what that means is you're comparing
-the methodology your client across different laboratories
-and that's going to give you a sense of how good that method is
-and maybe when its tender error could be of course what we talked about a lot in
-this class
-has really been QA/QC activities that you can do both
-reporting the results and in perfroming your measurememts
-and a lot of this week is gonna be touching
-on exactly these issues how you can use
-certified reference materials for quality control
-for managing an interest in your bias and of course for calibration
-will also talk again this week about uncertainty
-and a random error that you can get and how you report it
-and finally I think which are key study is all about
-is in getting you thinking about what is the
-end goal measurement and has your methodology
-is rife for that purpose a really important thing to keep in mind
-is that the state is that he is isn't just about let's say you need to measure
-something that Scott one part per billion you wanna go crazy and design a
-system that can measure
-oh I don't know parts per trillion you want to stir up
-match your method to the needs and the user and understand what after
-I wouldn't it bring one example to your attention kinda quality control
-we'll be talking about a lot this week and one girl a common thing that I've
-even done in the laboratory
-is a regular call quality control charts so what you see here
-is on different days of the week you might for example
-nationally-known let even this standard and this
-new standard will be see RM were certified reference material
-and as you can see the numbers you get are variable D-day
-so what are the things that your you see nothin' which bank
-wores pacify is the
-acceptable variation in your lap can take
-so this is an example the QC method
-extremely common didn't name any analytical laboratories both
-research and professional another important
-Idea it's a little bit higher level than just QA/QC an analytical laboratories
-isn't even palette analytical
-measurement so this term is really enternched in how the laboratory
-become certified to produce good analytical results
-it's not all about QA/QC I'd this sat %uh
-principles from the UK's standard organization
-which sets forth what they would expect to see analytical laboratory that was
-doing national and perhaps if he's
-in the government UK study this week that's particularly relevant because the
-CPSC's actually
-telling people how to do the measurement but these labs
-don't attack did she wake you see that's actually the last
-condition they have to have trained personnel there to suggest themselves to
-external assessments and tests on a regular basis
-and they have to basically be doing the right thing pretty rigorous way
-and said the concept about analytical measurement really is what a laboratory
-has to Chi
-if it wants to be a place that people can come
-and you reliable data particularly poor decision-making in government settings
-so
-that was just my quick thoughts about you a
-she see much of what we're talking about this week
-are specific things you do as an analyst that are really under quality control
-the quality control measures that you take
-for you right into procedures that help make your announces
-more reliable more precise and more accurate
-thanks so much and see you next time