ethanolic extract
of “kemuning” leaves using linoleic-thiocyanate
method showed antioxidant strength in the following
sequence of 10% “kemuning” > 1% vitamin E > 5%
“kemuning” > 1% of “kemuning” extract. Using 2,2-
diphenyl-l-picryl hydrazyl (DPPH) method, the IC50
of “kemuning” extract was 126.17 μg/ mL which is
15 times lower than the vitamin E (positive control)
8.27 μg/ mL. In addition, the acetone extraction of M.
paniculata showed inhibitory effect toward xanthine
oxidase (XO), tyrosinase and lipoxygenase (LOX)
where 100 μg/ mL of the acetone extract was able to
inhibit 10% of XO activity, 62% of LOX activity and
at 500 μg/mL, the acetone extract inhibited 72% of
tyrosinase activity (Chen et al., 2009).