ConclusionsIn summary, endometriosis is a debilitating disease that impacts the quality of life of adult and adolescent patients. Diagnostic delays are common and may lead to a decline in reproductive potential and fertility. A semi/non-invasive diagnostic biomarker would be a useful tool to identify patients early in the disease process and thus improving outcomes, including less pain and better fertility. A myriad of biomarkers have been associated with endometriosis; however, they are not sensitive and specific enough for use in screening. These potential biomarkers would reduce the cost of surgical intervention by early diagnosing the cases and thus improve clinical management of the disease. Therefore, more research is needed in this area of medicine.