INTRODUCTION
Propolis is a hard resinous substance prepared by honeybees
from plant exudates, beeswax and bee secretions. Propolis is
a traditional medicine with known biological activities, and
numerous studies have reported its versatile pharmacological
activities, including antibacterial, antifungal, antiviral,
anti-inflammatory, antioxidant and antitumor actions
(Banskota et al. 2001; Yang et al. 2010). Its activity depends
on its content and types of flavonoid, which are affected by
different geographical and climatic zones as well as the
extraction methods (Dimov et al. 1992; Cho et al. 2005;
Orsi et al. 2005).