MEDICATION CHANGES
We examined medication changes from baseline to 48 weeks in those individuals who took medication for hypertension or diabetes during the study. For antihypertension medication, 4 of 43 LCKD participants (9%) had an increase (new medication added or dosage of existing medication raised) and 20 (47%) had a decrease (medication discontinued or dosage lowered). In the O + LFD group, 9 of 53 participants (17%) had an increase and 11 (21%) had a decrease in antihypertension medication. For diabetes medication, 1 of 16 LCKD participants (6%) had an increase and 13 (81%) had a decrease, while 1 of 22 O + LFD participants (5%) had an increase and 15 (68%) had a decrease.