CLFM images of the cells incubated with
PNA
PNA
NFκb‑flu
NFκb‑flu
NFκB‑flu
for 4 h (Figure 4 row 2) showed no signals of
PNA
NFκb‑flu
in the cells, indicating that without MPOC
,
PNA
could not significantly penetrate into cells. Intense
signals from PNA
NFκB‑flu
inside the nuclei, intense signals from
MPOC
TAMRA
NFκB‑flu
in the cytoplasm of the cells incubated with
PNA
NFκb‑flu
plus MPOC
(Figure 4 row 3), implied
effective delivery of PNA
TAMRA
NFκb‑flu
into the cells by MPOC
,
and accumulation of the PNA
NFκb‑flu
and MPOC
in the
nuclei and cytoplasm, respectively. Noted that cells incubated
with only MPOC
TAMRA
TAMRA
(without PNAs) also showed the
uptake of the particles (Figure 4 row 4). Similar results were
observed for PNA
(Supporting Information, Figure S7).
random‑flu
TAMRA
TAMRA