Taken together, it would seem that a program of supervised aerobic exercise comprising indoor or outdoor walking, stationary cycle or cross trainer exercise in either group, individual or combined formats, performed three to four times weekly, undertaken at low to moderate intensity or at the participants preferred intensity, with sessions lasting 30–40 min is beneficial in the treatment of depression. This appears to be effective for a range of co-interventions including medication use, psychotherapy, behavioral interventions to aid adherence and electroconvulsive therapy. Programs should be of at least nine weeks duration.