Acute toxicity
Oral administration of D. reticulata extract at the doses of 250, 500, 1,000, and 2,000 mg/kg did not induce abnormal behavior in rats of both sexes. Normal body weight gains were observed in male and female rats as shown in Table 4. There were no animal deaths during 14 days after administration of the extract. Therefore,
the lethal dose of D. reticulata extract was higher than 2,000 mg/kg. No gross abnormalities of internal organs were observed in animal treated with D. reticulate extract.
Acute toxicityOral administration of D. reticulata extract at the doses of 250, 500, 1,000, and 2,000 mg/kg did not induce abnormal behavior in rats of both sexes. Normal body weight gains were observed in male and female rats as shown in Table 4. There were no animal deaths during 14 days after administration of the extract. Therefore,the lethal dose of D. reticulata extract was higher than 2,000 mg/kg. No gross abnormalities of internal organs were observed in animal treated with D. reticulate extract.
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