The concentration of the heavy metals are higher in the tissues than the recommended value, which suggest that the Kali river is, to a certain extent, a heavy metals polluted river, and the fish consumption are not completely safe for health. Therefore, further continuous monitoring of heavy metals concentration in fish will be needed in India. Increase in concentration of Cd and Cu in fish liver is greater than other organs. Cd and Cu at sublethal concentration in fish decreases survival growth and reproductive health and mainly accumulate in gills and liver (Beyer et al. 2000) [15]. Its bioaccumulation can decrease oxygen consumption. In several studies H. fossilis species obtained from different selected countries