Rabbits were fed a cholesterol diet with PB or CZ alone or both PB and CZ for 16 weeks.
The plasma levels of total cholesterol, LDL-cholesterol, HDL-cholesterol, C-reactive protein, superoxide dismutase, malondialdehyde, andnitricoxide (NO) were measured.The aortic atherosclerotic lesions were grossly and microscopically evaluated.Additionally, in vitro experiments were conducted using human umbilical vein endothelial cells.