Plasma samples for analysis of fluoxetine
and nor-fluoxetine levels were
available for 43 of the 49 patients assigned
to receive fluoxetine. Plasma
samples from 3 patients had no detectible
fluoxetine or nor-fluoxetine.
Exclusion of the data from these 3
patients did not substantially alter the
results of the analyses of time-to-relapse.
The average fluoxetine and nor-fluoxetine
levels for the remaining 40
patients were 409 (225) and 297 (154)
ng/mL, respectively; these levels are
comparable with those reported in studies
of obsessive-compulsive disorder