BMI at the time of entry had a more significant influence on
the risk of cesarean section, PIH or pre-eclampsia than did the
degree of abnormal OGTT results.
The limitations of this study were that the recorded data
were not extensive enough to be properly adjusted and that
BMI was recorded at delivery and not pre-pregnancy. Another
possible limitation might be that negative 50-g GCT individuals
might also be glucose intolerant on the 100-g test.
An additional limitation was that only a few individuals were
classified as Grades 3 and 4. In addition, other potential factors
led to adverse outcomes irrespective of diabetes. However, we
were able to demonstrate that there was an increased risk for
preterm labor and admission to the NICU as the abnormal
degree of OGTT results increased.
In conclusion, our results indicated an increased risk for
preterm labor and admission to the NICU as the abnormal
value of the OGTT increased according to the two-step
approach. These findings could provide evidence for the
development of an optimal approach to screening and diagnosis
of GDM [11]. Further research regarding the advantages
and disadvantages of screening and diagnosis of GDM are
needed.