Biomolecular motors offer self-propelled, directed transport
in designed microscale networks and can potentially replace pumpdriven
nanofluidics. However, in existing systems, transportation is
limited to the two-dimensional plane. Here we demonstrate fully onedimensional
(1D) myosin-driven motion of fluorescent probes (actin
filaments) through 80 nm wide, Al2O3 hollow nanowires of micrometer
length. The motor-driven transport is orders of magnitude faster than
would be possible by passive diffusion. The system represents a necessary
element for advanced devices based on gliding assays, for example, in labon-a-chip
systems with channel crossings and in pumpless nanosyringes.
It may also serve as a scaffold for bottom-up assembly of muscle proteins into ordered contractile units, mimicking the muscle
Biomolecular motors offer self-propelled, directed transportin designed microscale networks and can potentially replace pumpdrivennanofluidics. However, in existing systems, transportation islimited to the two-dimensional plane. Here we demonstrate fully onedimensional(1D) myosin-driven motion of fluorescent probes (actinfilaments) through 80 nm wide, Al2O3 hollow nanowires of micrometerlength. The motor-driven transport is orders of magnitude faster thanwould be possible by passive diffusion. The system represents a necessaryelement for advanced devices based on gliding assays, for example, in labon-a-chipsystems with channel crossings and in pumpless nanosyringes.It may also serve as a scaffold for bottom-up assembly of muscle proteins into ordered contractile units, mimicking the muscle
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