10. Conclusion These recommendations arose from careful consideration of an extensive body of higher quality evidence
derived from RCTs and systematic reviews and meta-analyses of RCTs. Rather than LDL–C or non-HDL–
C targets, this guideline used the intensity of statin therapy as the goal of treatment. Through a rigorous
process, 4 groups of individuals were identified for whom an extensive body of RCT evidence
demonstrated a reduction in ASCVD events with a good margin of safety from moderate- or high-intensity
statin therapy