Nanoparticles are formed from the emulsion droplets after organic solvent diffusion. The preparation of a stable
emulsion is crucial in order to avoid the coalescence of nanodroplets that occurs during the emulsification and
evaporation step. The use of a stabilizer plays an important role for the nanoparticle formation, as stabilizer remains
at the liquid–liquid interface during the diffusion process. In addition, lowering the interfacial tension between
aqueous and organic phases, this contributes to increased emulsion stability.