Table 2. As is evident from Table 2, most of the synthesized cordycepin existed in the culture filtrate and the other extracellular nucleic acid-related compound was only gua-nine. In the mycelia, several kinds of compounds were detected with the same level of cordycepin. These results indicate that the cordycepin synthesized by C. militaris is immediately and selec-tively secreted into its medium. The fact that adenosine was not observed in the filtrate indirectly supports the study by Lennon and Suhadolnik [37]. That is, the formation of cordycepin pro-ceeds by the enzymatic reduction of adenosine. Hereafter, it is not necessary to follow the compounds in the mycelia, since 98% of the synthesized cordycepin has been found to exist in the culture medium.