Particle formulations were suspended in 1X PBS and incubated in 2 mL dialysis
float-a-lyzers (3.5 KDa MWCO) while agitated at 37 C in 1X PBS under sink conditions.
Small aliquots were collected at various time points, replaced with fresh
solution, and analyzed by high-performance liquid chromatography (HPLC, Agilent
Technologies).