constituents may thus, be assumed to scavenge free radicals and exert a protective effect against oxidative damage
(induced damage) to cellular macromolecules. Drumstick leaves extract may also protect against oxidative injury
induced by diabetes in vivo and could thus be capable of enhancing and maintaining the activities of hepatic enzymes
implicated in combating ROS.
The in vivo as well as in vitro antioxidant studies of the aqueous extract thus, suggest that the presence of a number
of polyphenols, may be responsible for the antioxidant activity. Isolation and chemical characterization of the
leaves extract responsible for the antioxidant activity merits further study. Our studies on the antioxidant activity of the
aforementioned plant remedy are in progress for the isolation
of active constituents and to elucidate their mode of action
its ethnomedicinal use. In vivo antioxidant activity of
the leaves in diabetes-induced oxidative stress is being
reported in the present study for the first time. The extract’s