2.6. In vitro bacterial mutagenicity
Mutagenicity of TPM was assessed in the plate incorporation Salmonella Reverse Mutation Assay (Maron and Ames, 1983) according to the respective OECD guideline 471 (OECD, 1997a) as previously described (Roemer et al., 2012).
Determinations were performed in the presence and in the absence of a metabolic activation system.