Among the various structured mesoporous materials, cage-like large pore mesoporoussilicas (viz. mesocellular siliceous foam (MCF) [27] and hierarchi-cal mesocellular mesoporous silica (HMMS) [28]) with ultra-large mesocellular pores connected by meso-sized windows are supe-rior for immobilization of different enzymes due to higher loadingcapacity [29], low mass transfer resistance [30] and reduced leach-ing [31].