In order to quantify and evaluate the investment and the related energy saving that can be achieved through the optimization of plant systems, it have been considered as standard intervention the replacement of the existing boiler with a more powerful condensing boiler and the installation of thermostatic valves and room thermostats. This is done in order to minimize waste, for their crucial importance for energy costs and the subsequent need of immediate action on the control systems in relation to the difference between the estimated and real consumption of buildings. The analysis does not include the benefits obtainable by insulation of the pipeline as it is, in most cases, inside the buildings so that the advantages will be reduced considering that all the losses are inside of the buildings [19].