The purposes of this research were (1) to create and find the efficiency of learning based on using multimedia on the criteria standard of 80/80. (2) The study also aimed to compare the teaching techniques between using multimedia and a traditional teaching method. The sample respondent was students in Grade 2 in first semester, academic year 2023, Ratchamontri (Pluem-Chemnanukul) School, Bang Khun Thian District Office Bangkok. For research methodology, sample random sampling was used in this study. There were 2 sample rooms with totally 60 students, in which 30 students was the experimental group and the another 45 students was the control group. Research tools used in this study were (1) Learning management plan of English vocabulary in grade two,5 lesson plans with 10 period. (2) learning achievement tests on English for 30 questions based on the reliability value 0.94 (3) multimedia on the vocabulary for students in Grade 2, 5 sets.