The mission (flight and data acquisition) is planned in the lab with dedicated software, starting from the area of interest (AOI), the required ground sample distance (GSD) or footprint, and knowing the intrinsic parameters of the mounted digital camera. Thus fixing the image scale and camera focal length, the flying height is derived. The camera perspective centers (‘waypoints‘) are computed fixing the longitudinal and transversal overlap of strips, while the presence of GNSS/INS onboard is usually exploited to guide the image acquisition. The take-off and landing operations are strictly related to the employed vehicle and characteristics, but normally controlled from ground by a pilot (e.g. with a remote controller). During flight, the platform is normally observed with a control station which shows real-time flight data such as position, speed, attitude and distances, GNSS observations, battery or fuel status, rotor speed, etc. Most of the systems allow then image data acquisition following the computed ‘waypoints’, while low-cost systems acquire images according to a scheduled interval.