Due to the implication of the NgR complex in neurite outgrowth and
myelination processes throughout neurodevelopment, as well as the
genetic implication of NgR, WNK1 and Myt1l in schizophrenia susceptibility,
we sought to examine several SNPs of interest within NgR signaling
pathways in a selected case–control schizophrenia population,
factoring in early life stresses such as having a parental history of mentalillness or other traumatic events, to assess if genetic abnormalities with in these genes may have an association with early life adversity and
schizophrenia.