Renal Impairment : Lower initial doses and more gradual dosage increase.
Hepatic Impairment : Lower initial doses and more gradual dosage increase.
Administration : Should be taken with food.
Contraindications : Patients w/ reduced levels of CYP2D6 isoenzyme, congenital long QT syndrome or history of cardiac arrhythmias; severe CNS depression or comatose states of any cause; hypertensive or hypotensive heart disease of extreme degree. Concomitant use w/ drugs that prolong QTc interval, CYP2D6 isoenzyme inhibitors and drugs which reduce thioridazine clearance by other mechanisms.