The chemistry of natural compounds is a very complex subject and screening for activity will have to
face, among other factors, isolation and identification of the products, variability due to the plants or the
environment, and synergism due to mixtures of compounds in crude extracts. Our next approach will be to
concentrate efforts in a few more promising extracts to fractionate and isolate active compounds. According to
Cole (1994), the choice of insect and bioassay can greatly influence the outcome of a screening. However, to
develop a useful commercial product, testing against agricultural pests is important.