On an overall level only, successful scaling up of top-spray
fluidised bed coated particles by 48 times in weight from the
small-scale over medium-scale to the large-scale fluidised bed
has been achieved for flux number conditions of 4.5 and 4.7.
For the flux number values of 4.7 the scaling up was successful
irrespective of the nozzle pressure whereas only the highnozzle
pressure condition was successful for a flux number of
4.5. For these flux number values in general the agglomeration
tendency decreased with increasing flux number and increasing
nozzle pressure. For all other flux number conditions the
bed collapsed due to overwetting within the first minutes of the
coating process.