Uraemic xerosis may produce significant discomfort in some patients. In particular, it may provoke or exacerbate the bothersome symptom of pruritus, and be at least in part the cause of cutaneous complications including lichen simplex chronicus, prurigo nodularis and the secondary complication of impetigo [1]. Emollients should be used in MRD patients affected by xerosis with or without pruritus, either alone or in association with more specific anti-pruritic treatments.