A wild-typecrygene has a low G+C content, many potential polyadenylation sites , and numerous ATTTA sequences. It is expressed poorly in plants as a full length or as a
truncated gene. A synthetic type cry gene was designed by
mutagenesis with plant preferred codons, low A+T per-centage and increased G+C concentration. This synthetic
gene got expressed 500 times more than wild type in Trans-genic tobacco and showed complete protection toward beet