Antimicrobial Drugs of Choice on page 1840
Malaria Treatment on page 1859
Helicobacter pylori Treatment on page 1911
Treatment of Sexually Transmitted Infections on page 1861
Use Treatment of susceptible bacterial infections of both gram-positve and gram-negative organisms, also infections due to Mycoplasma, Chlamydia, and Rickettsia; indicated for acne, exacerbations of chronic bronchitis, and treatment of gonorrhea and syphilis in patents that are allergic to penicillin, as part of a multidrug regimen for H. pylori eradication to reduce the ask of duodenal ulcer recurrence
Pregnancy Risk Factor D
Pregnancy Implications Tetracyclines cross the placenta and enter ftat circulation ; may cuse permanent discoloration of teeth if used during the last hat of pregnancy.
Lactation Enters breast milk/not recommended (AAP rates “compatible”)
Medication Safety Issues
Sound-alike/look-alike issues :
Tetracycline may be confused with tetradecyl sulfate
Achromycin may be confused with actinomycin, Adriamycin PFS®
Contraindications Hypersensitivity to tetracycline or any component of the formulation; do not administer to children ≤8 years of age, pregnancy
Warnings/Precautions Use of tetracyclines during tooth development may cause permanent discoloration of the teeth and enamel, hypoplasia and retardation of skeletal development and bone growth with risk being the greatest for children