In this study, 0.25 lg/ml aflatoxin B1 was used to establish a liver cancer model for assessing the potential
anticancer ability of Chinese cabbage powder, which is a complex water-soluble extract from Chinese
cabbage by spray-drying at an outlet temperature of 130 C. We found at least 11 potential anticancer
substances in Chinese cabbage powder. A 90-d animal experiment demonstrated that 10% of Chinese cabbage
powder in drinking water could improve the plasma micronutrient status, inhibit the formation of
aflatoxin B1-DNA adducts in liver cells, and effectively reduce the incidence of liver tumor induced by
aflatoxin B1 from 6.67% to 0%. The dose effect experiment revealed that 10% may be the minimal effective
dose to prevent the occurrence of early liver tumors. This study will help elucidate the basis of epidemiological
observations of dietary cancer prevention in humans, as well as explore related mechanisms.
2015 Elsevier Ltd. All rights reserved.