According to the American cancer society, 2700 children and adolescents younger than 19 years old in the united states will be diagnosed with ALL in 2007 . Although the median age at diagnosis for all cases of ALL is 13 years, the peak incidence is between 2 and 5 years and is more predominant in male than females . There is a significant difference in race, with childhood ALL occurring more often among whites than blacks . Although there are few known risk factors associated with ALL, several genetic syndromes predispose one to the development of leukemia. Down syndrome is strongly associated with both childhood ALL and acute myeloid leukemia (AML). An increased incidence of ALL is also associated with other genetic disorders, including neurofibromatosis, Shwachman syndrome, Bloom’s syndrome, and ataxia telangiectasia