The study of crude extract from marigold found the most solvent that can be extraction of crude extract from marigold is Hexane then lead The extract obtained by extraction with Ben - Amotz and fishler method to detect carotenoids by measuring the absorbance found extract of solvents; Acetone and Ethanol contains carotenoids exist. And when tested UV protection with fibroblast cell and count cell that still alive to see the effectiveness in preventing cell UV rays found that the extract carotene carotenoids from the solvent Acetone can prevent UV. best by a cell number of live cells remaining from the 9051 total of 10,000 cells.