3. Results
3.1. Glycemic parameters
Blood glucose level in untreated STZ diabetic rats
(423.15 ± 49.28 mg/dl) was significantly higher than in the
non-diabetic rats (96.07 ± 2.76; p < 0.0001). Oral administration
of T. cordifolia (TC) suppressed the elevation of blood glucose level
to 352.22 + 47.78 mg/dl, which was significantly lower as compared
to diabetic control animals (p < 0.001), but was significantly
more (p < 0.0001) than normal rats.
Similarly, %HbA1c in diabetic rats (7.04 ± 0.18) was significantly
higher than normal animals (5.37 ± 0.48; p < 0.0001). However,
%HbA1c in TC treated group was 6.30 ± 0.90, which was significantly
lower than diabetic group (p < 0.05).