Centella asiatica has a reputation to restore decline cognitive function in traditional medicine and in animal model. However, little
evidence regarding the efficacy of Centella asiatica from systematized trials is available. Therefore, the present randomized, placebo-controlled,
double-blind study investigated the effect of Centella asiatica on cognitive function of healthy elderly volunteer.
Materials and methods: Twenty-eight healthy elderly participants received the plant extract at various doses ranging 250, 500 and 750 mg once
daily for 2 months. Cognitive performance was assessed using the computerized test battery and event-related potential whereas mood was assessed
using Bond–Lader visual analogue scales prior to the trial and after single, 1 and 2 months after treatment.