Process Route 2 (D in Fig. 3)
The process route consisted of batch fermentation followed by
centrifugation, LLE (with 2-ethyl-1-hexanol as extractant), and
steam stripping distillation. This design used C. acetobutylicum
PCSIR-10 as the fermentation strain, and will be referred to as
‘‘Process Design 2’’. The overall design of this process was based
on the process simulated by Dadgar and Foutch [12]. The batch fermentation
was based on the laboratory research results by Syed
[27], while the downstream processing design proposed by Liu
et al. [13] was adopted. The LLE process was based on similar unit
operations simulated in process designs by various authors
[1,12,13].