To efficiently and environment friendly combust the domestic garbage, sludge, and swill waste five different fuels are prepared by mixing the waste fuels together with coal, and grass biomass different mixing ratios, and finally those fuels were combusted in a circulating fluidized bed (CFB) reactor. The emission performances of NOx, dioxin, and heavy metal during the combustion tests studied. The results showed that the furnace temperature can be reached at approximately 850 eC combusting all studied mixed fuels, which could effectively improve the combustion performances of the waste fuels, benefiting the thermal processes of sludge and domestic garbage and thus realizing the purpose of waste-to-fuel. In addition, the dioxin emissions are much lower than the emission standards, and NOx emissions could be reduced significantly by adjusting the ratio of waste fuels. However, the emissions of mercury, lead, and the combinations of chromium, tin, antimony, cupper and manganese components all exceeded the pollution control standard for hazardous wastes incineration, a further technology is required for heavy metal reductions to achieve the emission standards.