Malachite green chloride is a triphenylmethane dye used in the fish and dye industries. Leucomalachite green is
prepared by the reduction of malachite green chloride. Malachite green chloride was nominated for toxicity and
carcinogenicity testing by the Food and Drug Administration and selected by the National Institutes of
Environmental Health Sciences for carcinogenicity testing by the National Toxicology Program (NTP) due to the
potential for significant worker and consumer exposure and lack of carcinogenicity data. The current 28-day
studies were conducted as part of an overall effort by the NTP to determine the toxicity and carcinogenicity of
malachite green chloride