RESULTS: Fucus extract was identified to have HO-1 stimulation activity at both gene and protein level. By stimulating this enzyme, it promotes the of toxic heme to its protective catabolites (CO,Ferritin, and bilirubin) and reduces the source of dark circles. In addition,Fucus extract showed good anti-inflammatory efficacy. The strong antioxidation property of Fucus extract can reduce eye bags and wrinkles while its collagen boosting activity will potentially reduce fine lines and wrinkles.
CONCLUSION: Fucus extract is a novel product that brings a quadruple approach to the treatment of under-eye dark circles