3.2. Anti-proliferative activities of MPEE
MPEE significantly inhibited the proliferation of A-431 and SKMEL-28 cells in a dose-dependent manner and a time-dependent
manner at higher concentrations (Fig. 1). MPEE showed less
cytotoxicity on human normal skin cell lines than human skin
cancer cells, as evidenced by higher EC50 values of 12.62 (on
CCD-1064Sk) and 8.32lg/ml (on HaCaT) compared to 5.07 (on