Meg Murry and Calvin O'Keefe. Meg's personal struggles at school and her inability to fit in with the crowd. This is also a problem for her younger brother Charles Wallace. Everyone thinks he is dumb, though both children are extraordinarily intelligent - indeed, Charles Wallace could easily be considered a genius. Beyond that, Charles Wallace also has the unique gift of being able to read the minds of others. Charles Wallace befriends a strange group of women living nearby - Mrs. Whatsit, Mrs. Who, and Mrs. Which. These three ladies soon take the children on a strange journey, promising to help them find and rescue their father who has been missing for two years. One afternoon, after meeting Calvin near the ladies' house, the three are swept off to another planet, Uriel, through the process of the tesser - the process of wrinkling space and time.