In 2002, Eiichiro Takeo and his group proved that the extraction of Luo Han Guo can effectively restrain the oxidation of low-density lipoprotein. So effectively dose 11-Oxo-mogroside V, whose ability of oxidation depends on the degree of dosage, that is when dosage is less than 50uM, 11-Oxo-Mogroside V will not display its capacity of anti-oxidation. In addition, 11-Oxo-Mogroside V also shows a certain ability of anti-oxidation to free-radical, but it is weaker than VE.