Folate belongs to the B vitamin group, and it is essential for cell growth, particularly during pregnancy when a low folate status (intake) increases the risk for neural tube defects (NTD) early in the pregnancy.(1) The classical human folate deficiency disease is megaloblastic anemia.(2) Other clinical aspects link a good folate status to protection against coronary heart disease, malformations, cancer, and cognitive functions, but the results from these studies are still not conclusive.(3-6) High intake of synthetic folic acid is investigated for cancer risks, but so far the results are not consistent.(6-8)