The extraordinary preventative or inhibitory effect of PL
against cancer is one of the most appreciated properties of PL. It is
also the main reason why PL attracts so much attention. In Japan, it has been reported that a patient suffered from hepatocellular carcinoma
with multiple lung metastases underwent a complete tumor
regression 6 months after taking the extract of PL mycelium, independent
of any other therapies In another case, the ingestion of
PL coupled with radiation therapy led to spontaneous remission of
hepatocellular carcinoma in a Korean patient which had metastasized
to the skull [14]. Furthermore, after taking the extract of PL,
the hormone refractory prostate tumor in a Japanese patient with the
bone metastasis shrank tremendously All these cases suggested
a linear relationship between the intake of PL and tumor
regression. Additionally, results from in vivo studies using mouse
models and in vitro experiments employing cultured cell lines have
reached to the consensus that PL possesses the anti-cancer potency
against a variety of murine and human carcinomas.