The present communication attempts to examine the possible antioxidant activities of ethyl acetate and alcohol extract from whole plant of Ruellia tuberosa
L. using in-vitro model. The ethyl acetate and alcohol extract from whole plant of Ruellia tuberosa L. were prepared and analyzed for antioxidant activity using
several methods such as DPPH (1,1-Diphenyl-2-Picryl-hydrazyl) radical, hydrogen peroxide (H2O2), superoxide radical, nitric oxide (NO) scavenging assay and
FRAP (Ferric ion reducing antioxidant power) assay. The IC50 value of ethyl acetate and alcohol extract from whole plant of Ruellia tuberosa L. for DPPH
radical scavenging assay was 64μg/ml & 55μg/ml, for hydrogen peroxide scavenging assay was 68μg/ml & 58μg/ml, for superoxide scavenging assay was 63μg/
ml & 60μg/ml, nitric oxide scavenging assay was 63μg/ml & 58μg/ml and Ferric ion reducing antioxidant power was 320μm/mg & 400μm/mg were determined.
The results showed higher antioxidant activities in all the methods for ethyl acetate and alcohol extract. The study suggests that Ruellia tuberosa L. might serve
as a good source of natural potent antioxidant activity. The results provide useful information on the pharmacological activities associated with free radicals
for this traditional folk remedy.