The present study aimed to assess the antioxidant effectiveness of different phenolic fractions prepared from apple peel using heat-induced fish oil oxidation. The specific objectives were: (1) to compare the recovery and yield of phenolic compounds extracted and fractionated from frozen and dried apple peel; (2) to examine antioxidant capacity of apple peel extracts and fractions using DPPH· scavenging ability and ferric reducing antioxidant power (FRAP) assays, and (3) to evaluate the ability of fractionated apple peel polyphenols in preventing fish oil oxidation as compared to commercial antioxidants.