In parents-reported quality of life, there was significant difference over time in total score (p=0.04) and in the self-esteem subscale (p=0.02) during the study period. Post hoc comparisons showed that the difference was significant between T1 and T2 for both of these measures (p=0.01 for both). There were no significant changes (p=0.10) in child-reported quality of life. The median child-reported score on the total scare was 64.5 (55.3–78.6), whereas the median parent-reported score on the total scale was 63.0 (57.5–73.5).