There is a research about a new mathematical model of logistics systems for solving the inventory cost in the wholesale businesses. The research is a study and a survey of logistics management for wholesale and retail businesses with six locations in four regional areas of Thailand. The objective of this research is an application of simple mathematical model to solve logistics management for wholesale and retail businesses. The results of the analysis found that respondents manage their inventories through feeling for their businesses. Also, the forecasting of the value of sales volume errors resulting in a backup product to sell is in high inaccuracy. This is an important issue that needs to be improved by using a mathematical model of the application of logistics management. We use warehouse management to be a data center management for purchases and sale management. The result of the development of logistics management finds that the stock value of the inventory reduces to 72 million baht approximately